Four years to the date, Brazil and Chile met with a trip to the 2010 World Cup quarterfinals on the line. Brazil won handily with a score of 3-0, only to drop their ensuing match with the Dutch days later.

It left Chile winless in three straight meetings with the powerhouse, each with the Brazilians scoring two or more goals.

With momentum and home-field advantage favoring the host nation this time around at the 2014 World Cup in the round of 16, the Chileans will again have a hard time finding their first victory against Brazil. They have not prevailed over the Brazilian team since 2000.

Still, they mave stand a chance if Brazil's history in the 2014 games is any indicator. Brazil has yet to hit their stride in this World Cup, games in which they were supposed to dominate, especially considering Group A's fragility. Selecao cruised to a 3-1 win over Croatia on June 12, but not before Marcelo scored on himself.  

In turn, Chile's road wasn't as easy, but they too persevered. La Roja joined Holland in dethroning Spain, shutting the defending champions out.

Coach Jorge Sampaoli's attack-first game plan made Chile a dark horse candidate. It's time to see if the same technique works against the perennial favorite.    

When: Saturday, June 28, 2014

Where: Estadio Mineirao, Belo Horizonte

Kick-off: 12:00 p.m. ET

Live Stream: ESPN Player, BBC iPlayer

TV: ABC

What to Watch For:

Injuries to Chile's key players - Central defenseman Gary Medel and midfielder Arturo Vidal are questionable going into Saturday's contest.

Medel has a muscle injury dating back to a tear he suffered with the Premier League's Cardiff City in February. Whether it forces coach Sampaoli to change his  3-4-1-2 formation remains to be seen.

The biggest threat in Chile's arsenal will hobble into the Round of 16.

Arturo Vidal was left out of Monday's tilt against the Netherlands but plans on playing against the Brazilians. He had right surgery last month and then injuries right Achilles heel during world cup play.

Vidal may not be close to 100 percent come match time, but his presence give Chile a much needed equalizer.

Stopping Neymar and Fred - After struggling through opening play, Fred scored a consolation goal against Cameroon. Look for him to have a breakout game.

Neymar is tied for top scorer through opening-round play and should draw double coverage from Chilean defenders, giving Fred breathing room.

Fred's at his best when he's cutting across the field rather than running down the middle, and he can't do so without Neymar at his side.

Prediction - Brazil will exploit Chile's injuries en route to a quarterfinals slot. Brazil 3-1

Projected Lineups:

Brazil (4-2-3-1): Júlio César, Marcelo, David Luiz, Thiago Silva, Dani Alves, Luiz Gustavo, Fernandinho, Neymar, Oscar, Hulk, Fred

Chile (3-4-1-2): Claudio Bravo, Gonzalo Jara, Gary Medel, Francisco Silva, Eugenio Mena, Marcelo Díaz, Charles Aránguiz, Mauricio Isla, Arturo Vidal, Eduardo Vargas, Alexis Sánchez