Both teams were the early favorites to win Group D and are now playing in what will be considered a knockout game. Italy is looking to come back after a surprising loss to the Costa Rican side. Italy will again rely heavily on Mario Balotelli.

When: Tuesday, June 24

Where: Estadio das Dunas Natal 

Schedule: ESPN2

Start Time: 9 a.m. PT

Live Stream: ESPN

What to Watch For:

The Italians will rely heavily on not only Balotelli but Andrea Pirlo. The Azzure will advance to the next round with a win or draw against Uruguay. Uruguay will rest their hopes on striker Luis Suarez.

The English Premiere League's leading scorer sat out the opener vs. Costa Rica recovering from knee surgery, but returned to score two goals against England.

Uruguay advanced to the semi-finals in the 2010 World Cup, and is looking to regain that form. 

Cavani and Forlan will need to show up big in this important match against Italy. Uruguay's captain Lugano is expected to sit out of the game with a knee problem. 

Predicted Lineup:

Italy: (4-5-1) Buffon, Abate, Barzagli, Chiellini, Darmian, De Rossi, Pirlo, Verratti, Marchisio, Candreva, Balotelli

Uruguay: (4-4-2) Muslera, A. Pereira, Gemenez, Godin, Caceres, M. Pereira, Gargano, Rodriguez, Arevalo, Suarez, Cavani