Multiple couples experienced relationship troubles on the latest episode of "Grey's Anatomy." 

On the episode, Arizona (Jessica Capshaw) tells Callie (Sara Ramirez) that she was with someone else during their separation. Callie lets it go once Arizona tells her that it's definitely over. But once Callie finds out she was sleeping with Leah, she gets very upset. Nevertheless, by the end of the episode Arizona convinces Callie to let her sleep in their bed instead of on the couch. 

Miranda (Chandra Wilson) is reluctant when Ben (Jason George) says that she should see a psychiatrist. Ben then confides in Derek (Patrick Dempsey), who is forced to take action because he's on the board of the hospital. Miranda is furious at her husband for talking to Derek about her personal issues. 

April (Sarah Drew) wants Jackson's (Jesse Williams) blessing before she goes through with her wedding. He gives her his blessing, then disinvites himself from the event. This raises Stephanie's (Jerrika Hinton) concerns, because she is wondering why they act so strange around each other if they are supposedly over each other. 

Also, Cristina (Sandra Oh) and Shane (Gaius Charles) share a kiss, and Emma (Marguerite Moreau) prepares a Thanksgiving feast for over 16 people. 

Meanwhile, Richard (James Pickens Jr.) fails his stress test and Derek keeps quiet about his wife's feud with Cristina when the subject arises. 

On the next episode, "Man on the Moon," April's sisters will arrive to attend her wedding. TVLine reports that her three sisters will be played by "Days of Our Lives'" Emily Happe, "Drop Dead Diva's" Elizabeth Bond and "The Middle's" Grace Bannon. 

The synopsis for the next episode reads: "April's [Sarah Drew] sisters arrive to help celebrate April's upcoming nuptials and quickly get on her nerves. Matthew [Justin Bruening] and Jackson [Jesse Williams] are forced to work together when they witness a terrible accident, Callie [Sara Ramirez] and Arizona[Jessica Capshaw] work hard to reestablish their relationship and Cristina [Sandra Oh] is pressured to live-stream an upcoming surgery. Meanwhile, a familiar face returns to the hospital, on Grey's Anatomy."

"Man on the Moon" airs Thursday, Dec. 5 at 9 p.m. on ABC.