The season premiere of spy thriller "Nikita" featured the titular character returning to the U.S. to clear her sullied reputation.

In "Wanted," Nikita (Maggie Q) is still on the run 100 days after the apparent assassination of the President of the United States. She has been on the run for the past three months while trying to figure out why the president shot herself.

Alex (Lyndsy Fonesca) has taken a position with the United Nations to stop human trafficking, which will also allow her to stop The Group's use of human test subjects.

Meanwhile, Michael (Shane West), Birkhoff (Aaron Stanford) and Ryan (Noah Bean) have been helping Michael get leads from their new headquarters, which is in an airplane.

Nikita comes back to the U.S. to talk to a journalist, who has been asking questions about the president's death. She is stopped by local police, and her reemergence makes the news.

She goes to NYC to talk to the journalist. She realizes that the president, the head of security and the German intelligence officer/Shop agent who bought the Black Box from Owen (Devon Sawa) were all acting out of character. She begins to think that some sort of drug may be to blame in all of the cases, and wants to use the journalist's source in the FBI to get blood test results.

However, the journalist doesn't have a source; he's been getting anonymous texts with information that has lead to the questions he's been asking. Nikita realizes that the texts are from Amanda (Melinda Clarke).

As she realizes this, the ENN building gets surrounded by local police. Nikita stages a hostage situation, holding the journalist at gunpoint. Her team comes to back her up. Birkhoff creates a photo of the FBI Deputy Director Graham's wife in a rifle's crosshairs, which Michael uses to inveigle him to help Nikita. The director calls for the power in the building to be shut down, and Nikita is able to escape through the vents.

Afterwards, Nikita tells Graham that she didn't kill the president. Graham pulls the car over and pulls his own gun out. When Nikita drives off, he shoots at her and hits her in the shoulder. Nikita then crashes the car, and tries to get to Michael on foot.

Graham gets the evidence Nikita left with the journalist, and then the tent the journalist was in explodes. It's revealed that Graham is working for Amanda and The Group, and is trying to frame Nikita for the deaths.

Meanwhile, Alex and Sonya (Lyndie Greenwood) are in India shadowing a government involved in human trafficking, where she also hopes to find intel about Amanda. Her attempt to get intel backfires, and only one of the people she's shadowing escapes alive.

Alex finds some Shop technology in the wreckage. Just as she's about to leave, she gets a gun pointed at her head by the Cleaner, who was known previously as Owen.

"Nikita" herself, Maggie Q, spoke to TVLine about the premiere episode, as well as what's in store for the rest of the spy saga's farewell season.

She said there is still animosity between Michael and Nikita. "He's [Michael] not healed," she said. "He's still in a place where he can't understand her decision. And she doesn't rekindle with the whole team [at first], just Michael, Birkhoff and Ryan. Her relationship with Birkhoff is like brother and sister, so at the end of the day there's so much love there. They're just relieved to see her. Birkhoff makes some comments about her leaving, offhandedly, but when he sees her, he's thrilled."

Q also said that Nikita will share some great moments with Birkhoff this season. "I've always loved Birkhoff and Nikita, and I believe episode four is really theirs, " she shared. "When Aaron [Stanford] and I were shooting that episode, it was funny how little things just came out, little nuanced things. There's a moment at the end of an episode this season where Birkhoff's been through a lot and Nikita comes to try to comfort him. They're just alone and there's this subtle, physical way that they are together where you see this really great friendship that started so long ago."

She also shared that Nikita and Amanda will come face-to-face at one point in the season. "It's really all about if Nikita and Amanda don't have closure with one another, neither of them is ever going to be okay. Nikita needs that relationship to come to something - either come to fruition or come to an end."

She revealed that a main character will die in season four. "We lose someone pretty big, but the sacrifice in it is so touching. When the script came to me, the director and I wanted to find a way to make this work - whenever somebody dies it's sad and touching, but this is more about the sacrifice and how big that really is when someone makes the decision to take one for the team, so to speak, and what that means for Nikita's heart," she shared.

Will Nikita find happiness in the end? "We don't completely wrap it up - Nikita's not holding her first-born in the last shot of the show. [Laughs] What I liked about how we ended it is that Nikita does not change. It's not like you see her as a different person who wants to settle down and be happy... You'll see. It slows down for her, but she's Nikita! So, the end is a little bit playful as well, which is cool," Q teased.

Lyndsy Fonesca also gave an inside scoop about what her character will face in the show's final season.

"Sam quickly comes into the picture, and we're going to [use that to] trick the audience a few times," Fonseca hinted. "After the rewiring Amanda did to Alex's own head, there's an understanding; she's trying to give Sam the benefit of the doubt. At first it's, 'Oh s-t, Sam's here. He's got a gun to me. This is bad.' But then maybe they're working together, and then he switches again and has a secret... For Alex, this relationship is all about finding Owen in him and reaching that person."

Fonesca also said that fans will be satisfied with Alex's ending. "I feel like [creator] Craig [Silverstein] and the writers really wanted her [Alex] to finally have some sort of happiness in the end and we're going to be able to see that."

On the next episode, "Dead or Alive," "Nikita (Maggie Q) reunites with Michael (Shane West), Birkhoff (Aaron Stanford) and Ryan (Noah Bean) aboard the team’s aircraft command center. Michael refuses to discuss their relationship but tells Nikita she should stay with the group and let them help her clear her name. Ryan realizes Amanda (Melinda Clarke) is making doubles of VIPs with The Shop’s help. Nikita discovers that one of the doubles is the Director of the FBI (guest star Alex Carter), but doesn’t know how to kill him without exposing herself. Meanwhile, Alex (Lyndsy Fonseca) holds Sam (Devon Sawa) at gunpoint and demands he return what he stole from her, but when a gang of thugs attacks them they are forced to work together to escape."

Watch the promo for "Dead or Alive" below, which airs Friday, Nov. 29 at 9 p.m. on The CW.